Karim Maghni, Ph.D.

Neuroimmunology of Asthma Laboratory
Centre de recherche
Hôpital du Sacré-Coeur de Montréal
5400 boulevard Gouin ouest
Montréal (Québec)
H4J 1C5

Fax: (514) 338-3123

Affiliated institution: U. de Montréal, Departement of Medicine

Email: maghnik@medclin.umontreal.ca

FRSQ research centre: Centre de recherche de l'Hôpital du Sacré-Coeur de Montréal

Web Page: www.axe-recherche-sante-respiratoire.org/maghni/en

TRAINING AND CREDENTIALS

Diploma / Credential | Specialty | Year | Institution

Postdoctorate	Immunology of Asthma	2000	U. McGill
Ph. D.	Pharmacology	1996	U. de Sherbrooke
Doctorate	Cellular Biology	1992	U. Montpellier 2- Languedoc
-	Biology	1987	U. Montpellier 2- Languedoc
-	Chemistry	1986	Éc.nat.sup.chimie, Montpellier
Master	Physical Chemistry	1984	U. Paris 7 - Denis Diderot
License	Physical Chemistry	1983	U. Paris 7 - Denis Diderot
-.	Chemistry	1982	U. de Rouen Haute Normandie

AREA OF EXPERTISE

Research field: RESPIRATION

Research sub-field: Asthma

Research field: Respiration

Research sub-field: Immunoregulation

RESEARCH ACTIVITIES

Key words: Asthma, neurokinins, CD4 T cells, cytokines, chemokines, neuro-immunomodulation

Research interests: To determine the interactions between the neurokinins and the immune system in
the physiopathology of asthma using neurokinin-deficient mice sensitized to an
allergen. Role of neurokinins in allergen-induced humoral response, airway
hyperreactivity and inflammation (cytokines/chemokines expression).

RECENT AND REPRESENTATIVE PUBLICATIONS

Authors

Title (article or book chapter)

Year | Volume | Number | Journal or book | City and publishing house

Maghni K, Taha R, Afif W, Hamid Q, Martin JG
«Dichotomy between neurokinin receptor actions in modulating allergic airway responses in an animal model of helper T cell type 2 cytokine-associated inflammation»
2000 162 3 pp. 1068-1074 Am J Respir Crit Care Med

Maghni K, Nicolescu OM, Martin JG
«Suitability of cell metabolic colorimetric assays for assessment of CD4+ T cell proliferation: Comparison to 5-bromo-2-deoxyuridine (BrdU) ELISA»
1999 223 2 pp. 185-194 J Immunol Methods

Maghni K, de Brum-Fernandes AJ, Foldes-Filep E, Gaudry M, Borgeat P, Sirois P
«Leukotriene B4 receptors on guinea pig alveolar eosinophils»
1991 258 2 pp. 784-789 J Pharmacol Exp Ther

LITTERARY OR ARTISTIC WORKS

LANGUAGE COMPETENCIES

Languages understood

Languages read

Languages write

Languages spoken

Français