5.1. Factors in the early occupational exposure phase

5.1.1. The host or worker

1. Role of sensitization to allergens in the general environment (moulds, pollens, etc.)
2. The possibility of specific sensitization to the agent in the workplace at this early stage
3. Developing new immunological methods for measuring sensitization (detection of activated basophiles, measurement of T lymphocyte proliferation)
4. Study of bronchial inflammation and remodelling in induced expectoration
5. Validation of respiratory health questionnaires
6. Use of new techniques for evaluating bronchial hyperexcitability
7. Conducting a complete psychosocial evaluation
8. Determining the best possible model for monitoring programs

5.1.2. The workplace

1. Improving techniques for quantifying sensitizing agents in the workplace (cassettes to be developed with the IRSST)
2. Additive effect of pollutants in the general environment (SO2, ozone)